VACCINES

Preventing a disease is always better than having to cure it,
but most of these vaccines were developed before bioterrorism
emerged as a threat, and few are widely available

BIOLOGICAL WEAPONS: AVAILABILITY OF VACCINES

DISEASE

SYMPTOMS
VACCINE'S EFFECTIVENESS
AVAILABILITY
Anthrax First signs of inhaled anthrax may resemble those of a common cold; then breathing problems, hemorrhage, edema and shock. Untreated, about 90% of cases are fatal An early version of the U.S. vaccine was 93% successful in protecting against the disease. Full treatment involves six shots followed by an annual booster Only to military personnel and others whose jobs put them at high risk; approved only for healthy adults between the ages of 18 and 65
Pneumonic Plague Fever, chills, weakness, shortness of breath, cough with bloody sputum. If not treated early, rapid onset of septic shock and death May prevent bubonic plague, but that is not the form of the disease that would likely result from a bioweapon attack. Pneumonic plague should be treated with antibiotics Recommended only for people who work with the plague pathogen, Yersinia pestis, or in plague-infested areas
Smallpox High fever, fatigue, severe headache and backache, followed by a characteristic rash and deep, round lesions. Highly infectious Given prior to exposure, provides almost 100% protection against the disease. Still effective up to four days after exposure Extremely limited. Not recommended since 1980, when disease was eradicated. The U.S. has a few million doses; 40 million more on order
Botulism Blurred vision, slurred speech, difficulty swallowing, progressive muscle weakness that spreads from head to toe, paralysis, respiratory failure Believed effective against five of the seven types of botulism toxin but still being tested Only on an experimental basis for those believed at high risk of exposure. The standard treatment is to administer antitoxin after exposure
Tularemia Abrupt onset of high fever, followed by pneumonia, pleuritis and systemic infection. Can lead to respiratory failure, shock or death. Highly infectious Provides partial protection against infection by inhalation or direct contact. Antibiotics are the treatment of choice Only given to people who work routinely with tularemia bacteria. Not yet approved by the Food and Drug Administration
From TIME Magazine, October 8, 2001



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