January 19, 2004
Health
L
L E A D
Lead poisoning doesn't seem like much of a problem these days,
but new research gives fresh cause for concern. It seems that
blood levels of lead previously thought to be safe can actually
cause intellectual impairment. Not only that, but quite a bit of
damage seems to occur at low levels of exposure. A five-year
study found that kids with a blood-lead level at the acceptable
threshold of 10 micrograms per deciliter (mcg/dl) scored seven
points lower on an IQ test than kids with a level of only 1
mcg/dl. The guidelines for safe lead levels have been revised
repeatedly over the years, from 60 mcg/dl before 1970 to 25
mcg/dl in 1985 to 10 mcg/dl. They may have to change again. The
CDC estimates that 1 in 10 children under age 6 has a blood level
of 5 mcg/dl or higher.
L O N G E V I T Y
Various studies have shown that identical twins live longer than
fraternal twins. Researchers think they know why: communication.
Identical twins appear to keep in touch by phone or mail more
often; such social support is known to improve health. The extra
bit of close contact translated into a median life-span of 82
years vs. 80.5 years for fraternal twins.
M
M A D C O W
Word came just two days before Christmas that the dreaded
disease, formally known as bovine spongiform encephalopathy
(BSE), had arrived in the U.S. Tests confirmed that a 6-year-old
dairy cow, which had been ground into hamburger two weeks
earlier, was a carrier. Although the cow had entered the U.S.
from Canada in 2001, more than 30 countries quickly banned U.S.
beef imports. The U.S. Department of Agriculture in turn recalled
10,000 lbs. of ground beef and instituted a series of measures to
reassure consumers, including a ban on the slaughter of cattle
too sick or injured to walk. The cow in question was born a few
months before a ban on feeding cattle the pulverized remains of
their kin, the most likely path of infection, went into effect in
Canada and the U.S. Only 20,000 of the 35 million cattle
slaughtered in the U.S. each year are tested for BSE.
O
O B E S I T Y
What will it take to get our attention? Obesity accounts for
280,000 deaths in the U.S. each year. If current trends continue,
the battle of the bulge will overtake smoking as the primary
cause of preventable death. Some researchers believe that today's
wide-bodied kids will have shorter life-spans than their parents.
The number of overweight kids has tripled in the past 20 years,
and some two-thirds of American adults are either overweight or
obese. Sure, stomach stapling is all the rage100,000 operations
last yearbut the costly, risky procedure is no answer for the
massive masses.
Meanwhile, the search is on for a magic pill. One study found
that a natural compound called PYY reduces appetite and food
intake when given to test subjects intravenously. Another study
found that a natural fatty acid, OEA (oleylethanolamide), also
seems to regulate hunger and metabolismat least in mice.
Research on both compounds is still in the early stages, but they
could be the basis for new treatments targeting obesity. What to
do until these wonder drugs arrive at the local pharmacy? Yep.
Eat less, and exercise more.
P
P A R K I N S O N ' S
The quaking, shaking symptoms of this degenerative disease, which
afflicts 1.5 million Americans, have been notoriously tough to
treat. For 40 years, efforts have focused on drugs that regulate
the function of a key neurotransmitter called dopamine. Now
attention is shifting. Doctors have begun implanting electrodes
on both sides of the brain to stimulate its inner regionsan
approach that has shown some success in treating intractable
epilepsy.
And a drug unrelated to dopamine, istradefylline, seems to reduce
tremors and slowness in Parkinson's patients with advanced
disease.
Given that the condition can only be slowed, not cured,
prevention may be the best bet. A long-term study of 140,000
adults suggests that regular use of nonaspirin painkillers such
as Motrin or Aleve may offer some protection. Another prevention
strategy is to avoid head injuries. Studies have shown that
individuals who have experienced a head injury serious enough to
require hospitalization have an eightfold higher risk of
suffering from Parkinson's disease later in life.
P A X I L
A group of antidepressants called SSRIs may be doing wonders to
lift moods in adults, but concern is growing over their use in
teens and kids. First, researchers in Britain found that
youngsters taking Paxil were more likely to have suicidal
thoughts. Regulators there decided the drug should not be given
to children. In the U.S. the FDA quickly followed suit. Six
months later, the British regulators warned against the use of
five other antidepressants in young people. Doctors on both sides
of the pond still think that Prozac is O.K., but expect the U.S.
to take a closer look at all other SSRIs.
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