January 19, 2004
Health
S
S A R S
The first reports of an unusual and severe form of pneumonia came
in February, from doctors in Hong Kong. In March, the brand-new
disease SARSsevere acute respiratory syndromeclaimed its
first victim in the island city. Soon SARS was suspected to have
infected more than 7,600 people in 30 countries, including
Taiwan, Canada and the U.S. Travel was restricted, schools were
shut down, and panicked residents of hard-hit countries wore
masks outside their homes if they went out at all. But by April,
with a swiftness the World Health Organization called stunning,
scientists had identified the novel virus at the root of SARSa
member of the coronavirus family, which usually causes nothing
more than a bad coldand sequenced the new pathogen's genome.
Chinese health officials were roundly criticized when it became
clear that the bug had actually made its first appearance late in
2002 in the southern Chinese province of Guangdong; a more timely
alert might have helped stem its spread. By year's end, U.S.
researchers had successfully tested an experimental SARS vaccine
in monkeys.
S M A L L P O X
Although smallpox was declared eradicated in 1980, the U.S.
government remains concerned that stocks of the virus might fall
into terrorist hands and be unleashed on the public. To counter
that scenario, federal scientists are testing a new generation of
safer vaccines (the old one is the most lethal vaccine around,
killing an estimated one or two of every million who take it) and
helping to fund a multimillion-dollar effort to create a pill to
treat and possibly prevent infection. The Bush Administration
last year offered a version of the old vaccine, on a voluntary
basis, to key civilian health-care workers. The initiative ground
to a halt in June after just 38,000 of the 500,000 intended
subjects were inoculated. There just weren't enough doctors and
nurses willing to risk a potentially fatal reaction.
S M O K I N G
Cigarettes are still bad for you, and it's still as hard as ever
to quit. But researchers have found two more good
reasonsparticularly for womento tough it out. A study of
3,000 smokers, ages 40 years and older, showed that female
smokers had twice the risk of lung cancer as their male
counterparts, independent of age or the amount they smoked.
Further, in a separate study of 5,300 smokers, scientists found
that giving up cigarettes benefits women more than men. In the
first year after quitting, the women's lung function improved
more than twice as much as the men's, and it stayed better
throughout the five-year study.
T
T R A N S - F A T T Y A C I D S
There's fat, and then there's trans fat (e.g., "hydrogenated"
oils)also known as trans-fatty acids. Food manufacturers began
using them in place of saturated fats in the 1980s. Trans fats
extended the shelf life of certain products, and foodmakers
thought they made edibles safer. Turns out trans fats, like
saturated fats, raise bad cholesterol (LDL) and may lower good
cholesterol (HDL). As if that weren't bad enough, they may also
increase the risk of diabetes. Current labeling guidelines don't
require manufacturers to state how many grams of trans fats are
in a product, but the FDA has called for food labels to come
clean. Look for trans-fat grams on all labels beginning Jan. 1,
2006.
V
V A C C I N E S
The threat of bioterrorism jump-started dormant plans to create
reliable vaccines against some of the world's deadliest agents.
In October U.S.-government scientists began their first human
trial of an experimental vaccine against Ebola, a lethal African
virus that triggers severe internal bleeding and kills up to 90%
of its victims. Experts have long feared that Ebola could be
turned into a devastating bioweapon. Meanwhile, at Harvard,
researchers created an anthrax vaccine that, unlike older
vaccines, targets both the toxins created by the bacterium and
the bug itself.
V I S I O N
There's a new Lasik in town. You remember the old Lasik, the eye
operation that improves vision by reshaping the cornea with
lasers. The new version is called wavefront-guided Lasik and
depends on technology developed by astronomers to correct
problems in high-powered telescopes. Wavefront Lasik uses 200
little lenses to map the cornea, taking into account all its
bumps and abnormalities to produce a highly accurate,
individualized prescription. Conventional Lasik, by contrast,
applies one standard formula to each eye. If the old Lasik is off
the rack, wavefront is a custom-fit procedure. Studies show that
the new method reduces the occurrence of common postsurgical side
effects, such as halos, glare and bad night vision. But the risks
of eye surgery still apply. Cost: up to $3,000 per eye.
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