Will the 21st century produce more important innovations than the last? Who will be the top inventors? Tell us if you agree with TIME's choices. Which of the following breakthroughs do you think will come first? The ability to clone humans A cure for cancer Extending the average life past 100 Other

Do you know the next Einstein? Is your neighbor working on the next great health breakthrough? If so, e-mail us the name of your nominee, explaining in 50 words or less why we should choose him or her.

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Animation Photographs: Gandhi by J.A. MILLS/AP PHOTO, FDR by ARTHUR ROTHSTEIN/CORBIS, Binoculars by BETTMAN/CORBIS, Beatles by AP PHOTO, Spielberg by KEVORK DJANSEZIAN/AP PHOTO, Einstein by AP PHOTO, VR by C. MOORE/CORBIS, Baby by PHILIP GOULD/CORBIS Test tubes by JIM WEHTJE / PHOTODISC, Guggenheim Museum in Bilbao by ROSMI DUASO, Palm Pilot by RICHARD DREW/AP PHOTO, Pie by BRIAN LEATART, Court facade and candles by PhotoDisc

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