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| CHRIS BJORNBERG/PHOTO RESEARCHERS |
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TAMOXIFEN
Most women treated for breast cancer take tamoxifen to prevent the cancer from recurring, but it seems that for the drug to be most effective, timing is key. Until last year, most women with early-stage, estrogen-sensitive breast cancer had surgery followed by chemotherapy and tamoxifen. Tamoxifen blocks estrogen's cancer-promoting effects, but it turns out that the drug keeps chemotherapy agents from penetrating cancer cells and destroying them. An eight-year study of breast-cancer patients showed that women who waited to take tamoxifen until after their chemotherapy cycles were complete were 18% more likely to survive without a recurrence of cancer than women who took the two treatments together.
Related Sources:
American Society of Clinical Oncology annual meeting (May 2002)
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