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How Much for this Gene?
Scientists and academics at Davos debate the price and patentability of genetic material


BY JEFF CHU Davos


JANUARY 27  
world economic forum
You didn't have to get the word "blastocyst" to understand that there was some serious disagreement at the WEF panel Friday on intellectual property and genetic material. Onstage to air and share were four luminaries from different parts of the scientific spectrum: Ian Wilmut, best known for cloning Dolly the sheep; Jeremy Rifkin, a science and technology trend-watcher; Ajay Piramal, head of an Indian pharmaceutical company; and Dorothy Nelkin, NYU professor of sociology and law and a specialist in the public impact of science.

At issue: when it comes to genetic material and DNA, what can be patented? Who holds the intellectual property rights to genes? Friday's forum was an extension of an ongoing debate among scientists, doctors, politicians and patients. And as Ellis Rubinstein, the Science magazine editor and moderator of the discussion, said, "It's only going to get more heated, in many, many ways."

To seat Wilmut next to Rifkin was to set the stage for combustion. Wilmut, an advocate of the right to patent genetic innovations, said that the extraordinary expense of research justified patents to permit experimentation to continue. He said that the price tag for lab work could rise "up into many millions more if we were to develop a product." Patents both help to attract capital and maintain a space in which scientists can work independently.

But such issues were beside the point for Rifkin, whose principal assertion was that genes cannot "belong" to anyone. He discussed the preparation of a global treaty "to make the gene pool a commons," with access to all scientists around the world. "There's a real question here about control over this raw resource for future generations," he said. "These genes don't belong to Brazil and they don't belong to Dr. Wilmut."

Nelkin pointed out that extraordinarily delicate issues are involved "when the patented object is part of the human body." She warned against the opening of a "technology bazaar" in which body parts can be "harvested like a crop, mined like a resource." And she acknowledged the concerns of various indigenous people groups, who have had their genetic material collected and analyzed by scientists. "Indigenous peoples are concerned about what they call biocolonialism," she said. There is a question of whether the samples taken "are useful to the people from whom the blood and genes are taken."

Piramal, chairman of Nicholas Piramal India, also asked questions about usefulness and argued that patents should only be granted when there is "an invention not a discovery." Moreover, the discovery "must be novel and useful." One of the problems with current patenting is that scientific innovations are often granted protection even before their utility is fully proven.

At times, things got personal. Wilmut criticized Rifkin for using "overly emotive" language, while Rifkin slammed the "runaway utilitarianism" reflected in the "whims and caprices" of those in research. "I am sure you loved your little sheep," he said to Wilmut, "but I think it sends the wrong message to our children."

Right and wrong, though, meant completely different things to the panelists. The sheer magnitude of the issues involved, not to mention the potential profits to a patent-holder who could exploit an innovation for commercial gain, raised a host of questions that could not possibly be dealt with in one session. "Right of ownership of one's own genetic material is not clear," Nelkin said. And if one thing is clear, it's that the debate is far from over.


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