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Do Something
The Gates Foundation sets the bar high with a $100 million AIDS research grant


BY JEFF CHU Davos


JANUARY 27  
world economic forum
It's not all talk, no action here in Davos. On Saturday, the Bill and Melinda Gates Foundation announced a $100 million grant to the International AIDS Vaccine Initiative (IAVI) for work on AIDS vaccine development. The gift, the foundation's third and largest donation to the IAVI, comes on the heels of an earlier announcement about the launch of clinical trials of a possible AIDS vaccine designed specifically for Africa.

The Gates Foundation has now committed a total of $126.5 million to the IAVI over the past three years. According to Patty Stonesifer, executive director of the Gates Foundation, this most recent gift is a "fiscal and political" challenge both to the business community and to governments around the world. "It seemed the right time to say, 'We'll be there as they scale up if you'll be there,'" she said.

The IAVI estimates that it will need $550 million to fund its work through 2007. So far, it has raised about half of that. Its first vaccine candidates began human trials last August, while initial testing of the new vaccine — to target the subtype A of the HIV virus most common in East Africa — will begin shortly in Nairobi. These early-stage trials are designed to gauge safety and to study the impact of the vaccine on a healthy human system. It will be at least four or five years at the earliest before a potential vaccine will be ready for full-scale Phase III testing.

The Gates grant is a rare and welcome concrete move at a meeting traditionally geared toward conceptual thinking and development of ideas. Part of the point of announcing the gift at Davos was to send a message to the global glitterati in attendance that something must be done. In a statement, Bill Gates said, "The leaders gathered here should go away from Davos with a unanimous and absolute commitment to the International AIDS Vaccine Initiative." They may or may not, but at least the example has been set.


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