Modern Homo sapiens is still evolving. Despite the long-held view that natural selection has ceased to affect humans because almost everybody now lives long enough to have children, a new study of a contemporary Massachusetts population offers evidence of evolution still in action.
A team of scientists led by Yale University evolutionary biologist Stephen Stearns suggests that if the natural selection of fitter traits is no longer driven by survival, perhaps it owes to differences in women's fertility. "Variations in reproductive success still exist among humans, and therefore some traits related to fertility continue to be shaped by natural selection," Stearns says. That is, women who have more children are more likely to pass on certain traits to their progeny.
Stearns' team examined the vital statistics of 2,238 postmenopausal women participating in the Framingham Heart Study, which has tracked the medical histories of some 14,000 residents of Framingham, Mass., since 1948. Investigators searched for correlations between women's physical characteristics including height, weight, blood pressure and cholesterol levels and the number of offspring they produced. According to their findings, it was stout, slightly plump (but not obese) women who tended to have more children "Women with very low body fat don't ovulate," Stearns explains as did women with lower blood pressure and cholesterol levels. Using a sophisticated statistical analysis that controlled for any social or cultural factors that could impact childbearing, researchers determined that these characteristics were passed on genetically from mothers to daughters and granddaughters.
If these trends were to continue with no cultural changes in the town for the next 10 generations, by 2409 the average Framingham woman would be 2 cm (0.8 in) shorter, 1 kg (2.2 lb.) heavier, have a healthier heart, have her first child five months earlier and enter menopause 10 months later than a woman today, the study found. "That rate of evolution is slow but pretty similar to what we see in other plants and animals. Humans don't seem to be any exception," Stearns says.
Douglas Ewbank, a demographer at the University of Pennsylvania who undertook the statistical analysis for the study, which was published Oct. 21 in the Proceedings of the National Academy of Sciences (PNAS), says that because cultural factors tend to have a much more prominent impact than natural selection in the shaping of future generations, people tend to write off the effect of evolution. "Those changes we predict for 2409 could be wiped out by something as simple as a new school-lunch program. But whatever happens, it's likely that in 2409, Framingham women will be 2 cm shorter and 1 kg heavier than they would have been without natural selection. Evolution is a very slow process. We don't see it if we look at our grandparents, but it's there."
Other recent genetic research has backed up that notion. One study, published in PNAS in 2007 and led by John Hawks, an anthropologist at the University of Wisconsin at Madison, found that some 1,800 human gene variations had become widespread in recent generations because of their modern-day evolutionary benefits. Among those genetic changes, discovered by examining more than 3 million DNA variants in 269 individuals: mutations that allow people to digest milk or resist malaria and others that govern brain development.
But not all evolutionary changes make inherent sense. Since the Industrial Revolution, modern humans have grown taller and stronger, so it's easy to assume that evolution is making humans fitter. But according to anthropologist Peter McAllister, author of Manthropology: the Science of Inadequate Modern Man, the contemporary male has evolved, at least physically, into "the sorriest cohort of masculine Homo sapiens to ever walk the planet." Thanks to genetic differences, an average Neanderthal woman, McAllister notes, could have whupped Arnold Schwarzenegger at his muscular peak in an arm-wrestling match. And prehistoric Australian Aborigines, who typically built up great strength in their joints and muscles through childhood and adolescence, could have easily beat Usain Bolt in a 100-m dash.
Steve Jones, an evolutionary biologist at University College London who has previously held that human evolution was nearing its end, says the Framingham study is indeed an important example of how natural selection still operates through inherited differences in reproductive ability. But Jones argues that variation in female fertility as measured in the Framingham study is a much less important factor in human evolution than differences in male fertility. Sperm hold a much higher chance of carrying an error or mutation than an egg, especially among older men. "While it used to be that men had many children in older age to many different women, now men tend to have only a few children at a younger age with one wife. The drop in the number of older fathers has had a major effect on the rate of mutation and has at least reduced the amount of new diversity the raw material of evolution. Darwin's machine has not stopped, but it surely has slowed greatly," Jones says.
Despite evidence that human evolution still functions, biologists concede that it's anyone's guess where it will take us from here. Artificial selection in the form of genetic medicine could push natural selection into obsolescence, but a lethal pandemic or other cataclysm could suddenly make natural selection central to the future of the species. Whatever happens, Jones says, it is worth remembering that Darwin's beautiful theory has suffered a long history of abuse. The bastard science of eugenics, he says, will haunt humanity as long as people are tempted to confuse evolution with improvement. "Uniquely in the living world, what makes humans what we are is in our minds, in our society, and not in our evolution," he says.