Use the Body's "Repair Kit"

Wit

h the life expectancy of average Americans heading as high as 75 to 80 years, it is our responsibility to do everything possible to protect the quality of life of the present and future generations. A critical factor will be what we do with human embryonic stem cells. These cells have the potential to cure diseases and conditions ranging from Parkinson's and multiple sclerosis to diabetes and heart disease, Alzheimer's, Lou Gehrig's disease, even spinal-cord injuries like my own. They have been called the body's self-repair kit.

Their extraordinary potential is a recent discovery. And much basic research needs to be done before they can be sent to the front lines in the battle against disease. But no obstacle should stand in the way of responsible investigation of their possibilities. To that end, the work should be funded and supervised by the Federal Government through the National Institutes of Health. That will avoid abuses by for-profit corporations, avoid secrecy and destructive competition between laboratories and ensure the widest possible dissemination of scientific breakthroughs. Human trials should be conducted either on the NIH campus or in carefully monitored clinical facilities.

Fortunately, stem cells are readily available and easily harvested. In fertility clinics, women are given a choice of what to do with unused fertilized embryos: they can be discarded, donated to research or frozen for future use. Under NIH supervision, scientists should be allowed to take cells only from women who freely consent to their use for research. This process would not be open ended; within one to two years a sufficient number could be gathered and made available to investigators. For those reasons, the ban on federally funded human embryonic stem-cell research should be lifted as quickly as possible.

But why has the use of discarded embryos for research suddenly become such an issue? Is it more ethical for a woman to donate unused embryos that will never become human beings, or to let them be tossed away as so much garbage when they could help save thousands of lives?

Treatment with stem cells has already begun. They have been taken from umbilical cords and become healthy red cells used as a potential cure for sickle-cell anemia. Stem-cell therapy is also being used against certain types of cancer. But those are cells that have significantly differentiated; that is, they are no longer pluripotent, or capable of transforming into other cell types. For the true biological miracles that researchers have only begun to foresee, medical science must turn to undifferentiated stem cells. We need to clear the path for them as rapidly as possible.

Controversy over the treatment of certain diseases is nothing new in this country: witness the overwhelming opposition to government funding of AIDS research in the early '80s. For years the issue was a political football--until a massive grass-roots effort forced legislators to respond. Today, the NIH is authorized to spend approximately $1.8 billion annually on new protocols, and the virus is largely under control in the U.S.

While we prolong the stem-cell debate, millions continue to suffer. It is time to harness the power of government and go forward.