Are You Man Enough?

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Testosterone is the substance that literally turns boys into boys in the womb. In the first weeks after conception, all embryos are technically sexless. Around the sixth week of gestation, the presence of the Y chromosome in males triggers a complex set of signals that cause a surge in testosterone. Among other things, that sets in motion the formation of the penis and testes. In adolescence, boys undergo another eruption that deepens their voices, causes hair to form on their bodies and allows their muscles to enlarge. Testosterone in the blood of teenage boys can jump to as high as 2,000 nanograms, which helps explain teenage boys.

One possible danger of easy-to-use testosterone is that it might become a temptation to younger males looking to bulk up at the gym. Not many of them would be able to demonstrate the diminished T counts that would allow them to get it legally from their doctors, but the potential for a black market in AndroGel is not hard to imagine among teens and guys in their 20s--and older--who hear stories about a new substance stronger than the supplements available over the counter and easier to use than anabolic steroids that are injected. For teens in particular, the dangers of testosterone overload are not just acne and breast development but a shutting down of bone growth--though they may be at an age that makes them almost deaf to the risks. For older men, studies indicate that high levels of T do not necessarily cause prostate cancer but do fuel the growth of tumors once they occur, which is why chemical castration is one means of treating the disease in the advanced stages.

Gay men may have been one of the first populations to talk up testosterone replacement, which is often part of the treatment regimen for HIV-positive men like Sullivan, author of the New York Times Magazine piece. They produced a buzz about increased sex drive and better results at the gym, things that happen to be of interest to a lot of straight men too, especially middle-age baby boomers looking to put themselves back in the driver's seat as far as their sex drive is concerned. "These men already come in asking for [testosterone]," says Dr. Louann Brizendine, co-director of the program in sexual health at the University of California, San Francisco. "This generation came out of the sexual revolution. They really identify themselves as sexual beings. And they don't want to give that up."

At 66, Gene Teasley, who operates a family business that makes banners in Dallas, is a decade older than the baby boomers, but he gets the idea. About nine years ago, he went to his doctor complaining of less interest in sex. Since then, he has been getting testosterone shots once every two weeks. "I've enjoyed the results not just in the sexual way but also in a broader way of feeling healthier. I have more of a desire to work out, be outdoors and do more athletic things," he says. "Everybody wants to feel like they felt in their 20s and 30s."

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