Monsters, Inc., 2001
In Monsters, Inc., Pixar answered the age old question of whether or not there are monsters in our closets (yes there are, albeit by way of an interdimensional transporter.) This sweet fable about the perils of surrogate parenting follows the giant blue-haired Sulley (John Goodman) and his eyeball pal Mike (Billy Crystal) as they look after a two-year-old girl nicknamed "Boo" who unsuspectingly enters their monster world.

• 2011 TIME 100: John Lasseter