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Erythropoietin is usually the drug of choice for bloodless
medicine because of its stimulative effect on red-blood-cell
production. Hormones and vitamin B12 are also prescribed to
encourage cell production. Doctors may employ a hyperbaric
chamber to flood patients' blood with higher concentrations of
oxygen so that they can better withstand surgical procedures and
low blood levels, while oximetry devices and other noninvasive
monitoring equipment keep close watch over oxygen levels.
During surgery, bloodless practitioners often do everything they
can to stave off any blood loss that might require a
transfusion. Among the techniques: cryosurgery to freeze tissue
to be removed, or use of a harmonic scalpel, a vibrating laser
that simultaneously cuts tissue and clots blood. Brain surgeons
treating tumors and repairing blood-vessel malformations are
also using a state-of-the-art gamma "knife" that delivers a high
dose of radiation to precise points in the head through tiny
holes in a helmet that resembles a salon hair dryer.
Still, except for such techniques as radiosurgery, virtually no
surgery is completely bloodless. The blood that is shed during
operations at places like Englewood may be suctioned out by
cell-saving machinery, cleaned and then returned to the
patient's body. Red blood cells can also be saved through
hemodilution. In this procedure, hemoglobin-rich blood is pumped
unit by unit from a vein and replaced by an equal number of
units of a nonblood fluid to expand the volume to normal; the
patient's own drawn blood is held for use after surgery. In
another technique, doctors may use albumin, a protein found in
plasma that is acceptable to many who refuse transfusions on
religious grounds, to maintain or increase blood volume, or to
manage an underlying medical condition. Says Shander: "They used
to tell us, 'Give 'em a couple of bottles of blood--it won't
hurt; it's good for what ails them.' Well, that might be easier,
but I've learned to rely on less, with better results."
Since the Englewood program began in 1994, it has performed more
than 1,500 bloodless procedures, twice that of any other
institution. Most of them have been major operations that
usually involve extensive blood loss and transfusions: liver
resections, hip replacements, abdominal aortic aneurysms,
hysterectomies and brain surgery. "From a medical point of view,
there are no technical barriers to performing bloodless
surgeries," says Dr. Sharo Raissi, a cardiac surgeon at Brotman
Medical Center, one of a dozen hospitals in Los Angeles that
offer such services. "There is no limit as to what can be done
for patients, from open-heart surgery even to transplants."
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