The 2008 TIME 100

It is one thing to talk about the problems of the world and quite another to actually try to change things.

As a team, actors Brad Pitt, 44, and Angelina Jolie, 32, have served as our goodwill ambassadors worldwide. They brought help to Pakistan in 2005, after a catastrophic earthquake killed tens of thousands of people and left millions homeless. They have tended to the poor and sick in Africa. And they've raised global awareness—and contributed $1 million of their own money—for the victims of atrocities in Darfur. Brad co-founded Not on Our Watch, an organization set up to focus global attention on Darfur and other hot spots.

In the U.S., Brad and Angelina didn't just talk about, or even just throw money at, the tragic fallout from Hurricane Katrina. They actually moved to New Orleans and have set about trying to make right what so many have made wrong. Brad established a project to finance and build 150 new homes in the Ninth Ward.

Angelina has worked tirelessly through the United Nations on behalf of refugees around the world, touring border camps in Africa, Asia and Latin America and lobbying on Capitol Hill. The couple cares for three adopted children, from Cambodia, Ethiopia and Vietnam, in addition to their biological daughter.

There are hundreds of people who could be honored for their good works, but I've seen Brad and Angelina firsthand, and their commitment together is truly impressive.

Clooney is actively engaged in trying to resolve the Darfur crisis