The 2010 TIME 100

Marc Jacobs is undoubtedly one of the most influential designers of all time. He has never followed fashion or trends; he follows his heart and sets trends. His passion for popular culture infuses his designs with irreverence, color and energy. It's what sets him far ahead of his peers. He is not afraid to go against the grain and never feels the pressure to conform.

Marc, 47, is one of the most interesting and intellectual men I have ever known. He inspires and educates me every time we meet. He changes how we see fashion with each collection he shows, be it his work for Louis Vuitton or his own baby, the Marc Jacobs line, which he started in 1986. He finds beauty all around him, and his aesthetic is like no other. You can always tell when someone is wearing Marc Jacobs.

Beckham is a music artist, fashion designer and model

TIME 100 Social-Networking Index: 275,689