Persons of the Year 2005

Bill Gates, Melinda Gates and Bono: three people on a global mission to end poverty, disease — and indifference

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George W. Bush & Dick Cheney

BROOKS KRAFT / CORBIS FOR TIME

After winning re-election and claiming a mandate, the President and his No. 2 quickly squandered their political capital. Social Security reform, Iraq, Harriet Miers, Hurricane Katrina, the CIA-leak case, torture — on issue after issue, Bush and Cheney stumbled and saw their popularity drop. Although the team's numbers are improving somewhat, Republicans are facing next fall's midterm congressional elections with trepidation.

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