NATION | WORLD | BUSINESS | ARTS | PHOTOS | CURRENT ISSUE
Eric Lander
Scientists &
Thinkers
Edward Witten
Steven Pinker
Eric Lander
Korean Cloners
Paul Ridker
Hernando de Soto
Jeff Sachs
Linus Torvalds
Niall Ferguson
Bernard Lewis
Tariq Ramadan
Jurgen Habermas
Samantha Power
Sandra Day O'Connor
Jill Tarter
Julie Gerberding
Joschka Fischer
Bjorn Lomborg
Jong-Wook Lee
Louise Arbour

Leaders &
Revolutionaries


Artists &
Entertainers


Builders &
Titans


Heroes &
Icons


Introduction

Essay

FROM THE ARCHIVE: Scientists & Thinkers from 1900-1999

Unraveling the Threads of Life

By Philip Elmer-DeWitt

JASON GROW FOR TIME
 FROM THE TIME ARCHIVE
Human Genome Project
What We Should Worry About [7/3/2000]

When President Bill Clinton hosted an event at the White House four years ago to celebrate the end of the race to decode human DNA, the headlines belonged to the leaders of the two competing teams: J. Craig Venter and Francis Collins. But everyone in the room knew that the unheralded star of the race was the big teddy bear of a man sitting in the fourth row.

It was Eric Lander, while working for Collins in the tortoise-paced Human Genome Project, who saw that his team was losing and made it his business to beat Venter's harelike private venture at its own game. With $34 million from the Genome Project and a $38 million loan from M.I.T.'s Whitehead Institute, Lander ordered dozens of special-purpose computers and state-of-the-art capillary machines and built a huge automated gene-sequencing pipeline so insatiable that he was soon grabbing long stretches of DNA from other labs to feed its monstrous appetite. It was his lab's work that brought the race to a photo finish, and it was his name that appeared first on the Nature article that published the results.

Lander, 47, a math prodigy who learned genetics in his spare time, has always seemed a little larger than life. He was valedictorian of his class at brainy Stuyvesant High School in New York City, took first place in the Westinghouse Science Talent Search, graduated first in his class at Princeton and earned a Ph.D. in math as a Rhodes scholar at Oxford. He was teaching economics at Harvard when he started reading about DNA. "Suddenly it was clear to me that all the beautiful complexity of life had simplicity at its core," he says. "This is the kind of thing mathematicians love." Today Lander is leading the effort to use the new genetic tools to find treatments for ancient human diseases. At the Broad Institute in Cambridge, Mass., which he founded and directs, he is bringing together M.I.T. engineers who can navigate the genetic code and Harvard doctors who understand cancer, infectious diseases and psychiatric illness. It's an enormous challenge — just Lander's size.



Feb. 17, 2003 Sept. 10, 1984 April 29, 1991
Larger Cover
Larger Cover
Larger Cover

ADVERTISEMENT


Quick Links: Leaders & Revolutionaries | Artists & Entertainers | Builders & Titans | Scientists & Thinkers | Heroes & Icons | Back to TIME.com Home

FROM THE APRIL 26, 2004 ISSUE OF TIME MAGAZINE; POSTED SUNDAY, APRIL 18, 2004

Copyright © 2004 Time Inc. All rights reserved.
Reproduction in whole or in part without permission is prohibited.

Subscribe | Customer Service | Help | Site Map | Search | Contact Us
Privacy Policy | Terms of Use | Reprints & Permissions | Press Releases | Media Kit