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---
title: Is It Dangerous to Keep Getting COVID-19?
description: Common as they are, reinfections may come with lasting impacts.
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author: Alice Park
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article:published_time: 2024-01-10T15:19:38.000Z
article:modified_time: 2026-01-19T09:58:56.000Z
article:section: Health
og:title: Is It Dangerous to Keep Getting COVID-19?
og:description: Common as they are, reinfections may have lasting impacts.
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og:image:alt: Close-up of a hand holding a positive antigen test for COVID-19.
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twitter:title: Is It Dangerous to Keep Getting COVID-19?
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![](https://static.time.com/v3/assets/bltea6093859af6183b/blt77c90ecccba22b66/698a43afcabb1d4fbfe521a3/GettyImages-1362359164.jpg?branch=production&width=1200&quality=75&auto=webp&crop=16:9)


# Is It Dangerous to Keep Getting COVID-19?

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## TIME Health Matters: Reference Facts and FAQ

### Definition

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#### What is TIME's health newsletter?

Health Matters is TIME's daily health newsletter, written by TIME's health journalists. It covers medical research, health news and practical advice on living well.

#### Where can I get reliable health news by email?

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<!-- video src="https://cdn.jwplayer.com/manifests/TWdGwYtD.m3u8" -->
## Video: Former U.K. Prime Minister Boris Johnson Apologizes In Front of COVID-19 Inquiry Panel

[Watch (HLS stream): Former U.K. Prime Minister Boris Johnson Apologizes In Front of COVID-19 Inquiry Panel](https://cdn.jwplayer.com/manifests/TWdGwYtD.m3u8) (4:43)

![Former U.K. Prime Minister Boris Johnson Apologizes In Front of COVID-19 Inquiry Panel](https://cdn.jwplayer.com/v2/media/TWdGwYtD/poster.jpg?width=720)

_Published 2023-12-06. The U.K’s COVID-19 Inquiry into the government’s response to the pandemic picked up again on Wednesday morning. The hearings for the initial stage of the investigation were heard in London in June. Today, former U.K. Prime Minister Boris Johnson, who served as the nation’s leader from 2019 to 2022, was sworn in to give evidence in front of the panel. Shortly into his opening statement, he said that he was sorry for the suffering experienced by COVID victims and their families._


![Alice Park](https://static.time.com/v3/assets/bltea6093859af6183b/blt9b1ff6b12c3a4c3f/698a0b4397cdff3e366ba723/200116_Time_Headshots_Day552832-e1583529256299.jpg?branch=production&width=1200&quality=75&auto=webp&crop=1:1)

by 

[Alice Park](https://time.com/author/alice-park/)


![Alice Park](https://static.time.com/v3/assets/bltea6093859af6183b/blt9b1ff6b12c3a4c3f/698a0b4397cdff3e366ba723/200116_Time_Headshots_Day552832-e1583529256299.jpg?branch=production&width=96&quality=75&auto=webp)

## Alice Park


Senior Correspondent

Updated: Jan 19, 2026 9:58 AM UTCPublished: Jan 10, 2024 3:19 PM UTC

![Close-up of a hand holding a positive antigen test for COVID-19.](https://static.time.com/v3/assets/bltea6093859af6183b/blt77c90ecccba22b66/698a43afcabb1d4fbfe521a3/GettyImages-1362359164.jpg?branch=production&width=1200&quality=75&auto=webp&crop=3:2)

Close-up of a hand holding a positive antigen test for COVID-19\. SARS-CoV-2 antigen rapid test kit.

Close-up of a hand holding a positive antigen test for COVID-19\. SARS-CoV-2 antigen rapid test kit. Getty Images

![Alice Park](https://static.time.com/v3/assets/bltea6093859af6183b/blt9b1ff6b12c3a4c3f/698a0b4397cdff3e366ba723/200116_Time_Headshots_Day552832-e1583529256299.jpg?branch=production&width=1200&quality=75&auto=webp&crop=1:1)

by 

[Alice Park](https://time.com/author/alice-park/)


![Alice Park](https://static.time.com/v3/assets/bltea6093859af6183b/blt9b1ff6b12c3a4c3f/698a0b4397cdff3e366ba723/200116_Time_Headshots_Day552832-e1583529256299.jpg?branch=production&width=96&quality=75&auto=webp)

## Alice Park


Senior Correspondent

Updated: Jan 19, 2026 9:58 AM UTCPublished: Jan 10, 2024 3:19 PM UTC

Getting COVID-19 today is much less scary and more common than it was three years ago. By now, many people have had it not just once, but two, three, or even more times. Most of the time, repeat infections aren't as severe as they were the first time, leading to a sense of complacency about getting COVID-19 over and over. 

But reinfections aren't harmless. As cases continue to rise and more [variants arrive on the scene](https://covid.cdc.gov/covid-data-tracker/#variant-summary), infectious-disease experts are warning that repeat infections could have cumulative, lasting effects.

“There is some early evidence starting to show that if you had COVID-19, there can be all sorts of problems after getting infected” and reinfected, says Dr. Robert Murphy, professor of medicine and executive director of the Havey Institute for Global Health at Northwestern’s Feinberg School of Medicine. “We are just at the beginning of learning about them.”

## A higher risk of Long COVID

Dr. Ziyad Al-Aly, clinical epidemiologist at Washington University in St. Louis, [studies Long COVID](https://time.com/6232103/covid-19-reinfections-effects/): a condition marked by health effects that linger after infection. “Reinfection remains consequential,” he says. 

In a [paper published in Nature Medicine](https://pubmed.ncbi.nlm.nih.gov/36357676/) in 2022, he found that people who had gotten COVID-19 at least twice experienced higher rates of short- and long-term health effects, including heart, lung, and brain issues, compared to those who were only infected once.

### More From TIME


But why? Dr. Davey Smith, a virologist and head of infectious diseases at University of California San Diego, says that certain characteristics—such as older age—may make people more vulnerable to complications after repeat bouts. “The older you get, the worse you do with viruses in general, but specifically with SARS-CoV-2,” he says. “Every time you get COVID-19 again and again, you increase the likelihood of having a worse infection just based on age."

Underlying health conditions that people may not necessarily be aware of—like prediabetes or increased inflammation—could also put them at higher risk after each infection. “For somebody who is already on the edge of developing diabetes and then gets COVID-19, that could damage the pancreas and the endocrine system enough to change things,” Smith says. Similarly, having high rates of inflammation before COVID-19 could raise the risk of heart events such as stroke or a heart attack after an infection.


Regardless of a person's health status, each COVID-19 infection can raise the risk of developing blood clots, which can travel to the brain or lungs. That’s why Smith believes anyone who is eligible for antiviral drugs such as [Paxlovid](https://time.com/6553027/paxlovid-for-young-healthy-adults/) should take them, since controlling the virus as quickly as possible can reduce any potential long-term or lingering effects an infection can have on the body.

## COVID-19 may alter the immune response

At this point, many people view COVID-19 as relatively benign. But even if you've already recovered from a mild case, there's no guarantee that next time will go as smoothly. "Just because you did okay with it last year doesn’t mean you’ll do okay with it this year,” Smith says.

“There is a mischaracterization in the public understanding that you can get an acute infection with fever, cough, malaise, and fatigue, get over it after a few days or a week or so, then bounce back, and it’s gone,” says Al-Aly.“The data are showing that \[some\] people still display increased risk of problems even two years after an infection.”


That’s what he found in his study. People who had multiple infections were three times more likely to be hospitalized for their infection up to six months later than those who only got COVID-19 once, and were also more likely to have problems with clotting, gastrointestinal disorders, kidney, and mental-health symptoms. The risks appeared to increase the more infections people experienced.

Understanding why SARS-CoV-2 has a uniquely lasting effect on the body remains a challenge. Historically, when the immune system meets a new pathogen like a virus, it generates novel defenses and remembers the intruder, so it has a head start if the virus returns. That’s certainly the case with SARS-CoV-2—which is why vaccines work, and why getting reinfected generally leads to milder symptoms. 

But there is also growing evidence that in some people, getting COVID-19 the first time may compromise the immune response in a way that makes the body less likely to respond effectively the next time it sees the virus. That could leave certain organs and body systems, such as the [brain](https://www.abstractsonline.com/pp8/#!/10619/presentation/69863), weaker for months after infection—and subsequent ones. “It’s the balance of these two opposing forces—the immune system learning from the past and knowing how to deal with a virus and do a better job the second and third time around, and the idea that a first encounter with a virus might alter the immune system in some way that it becomes less efficient—that could explain why some people get Long COVID,” says Al-Aly.


Data also continue to show that even vaccinated people can get Long COVID—although the risk may be lower—since the protection provided by vaccines wanes over time, just as it does from infections. Vaccines are therefore a strong but not absolute barrier to the virus.

## Preventing reinfections

“Each time you get hit, it does impact your body, so let’s try not to get it too many times,” says Smith. That’s easier said than done, since after three years, people are tired of taking precautions such as wearing masks and avoiding crowded public spaces. “We’ve lost the public-health battle; there is no appetite for public masking or stringent public health measures,” says Al-Aly. 

That means other strategies need to become available, including universal vaccines that can protect against multiple variants and [nasal spray vaccines](https://time.com/6226356/nasal-vaccine-covid-19-us-update/) that stand guard at the nose, which is where SARS-CoV-2 generally enters. Researchers are currently testing these next generation shots, so while “the good news is that these technologies do exist, they need to be accelerated and brought to market as soon as possible to protect the public,” says Al-Aly.


In the meantime, Smith says it’s important for people to understand that they still need to do everything they can to avoid getting COVID-19\. That means staying up to date with vaccinations and taking some basic precautions, such as wearing [high-quality masks](https://time.com/6139169/n95-best-mask-omicron-covid-19/) indoors when cases are high, especially in crowded places and on public transportation.

“I wish we lived in a world where getting repeat infections doesn’t matter," says Al-Aly, "but the reality is that‘s not the case."


## Transcript

I thought I understand the feelings of these victims and their families and I am deeply sorry for the pain of the loss and the suffering of those victims and their families and grateful. I am to the hundreds of thousands of healthcare workers and many other public servants. Mm. people who walks of life to protect our country drive to Draper pandemic. I do hope that this inquiry will help to get the answers to the very difficult questions that we can do next time. He's alright we are asking for the avoidance of doubt and make it happen. So you can I haven't removed any walks apps from my but I'll give you everything good.

I think you need we may have made mistakes. I think it. I didn't want to try to anticipate the discussion, which I'm sure we will get into about the timings of NPR's lockdowns. It inevitably we got something's wrong. I think we were doing our best to the other time when you give him the information how to find the whole time. I think we we did our level best. Well, that seems we should have done differently. Unquestionably but you know, I would I would struggle to to itemize to move before you not in in in in in in a hard Rocky take personal responsibility fee. Do you take responsibility for whatever my lady makes of the speed of the government's response in January February March of 2020 and the way in which the various moving parts of the government's the advisory committee is the Department's the agencies and so on responded.

Do you take responsibility for the lockdown decisions whichever way they went and the timeliness of them? The manner in which patients were discharged from hospital into the castle actor. the explosion of the virus within the Residential Care Center the general speed at which the restrictions were released. the attack to help Heights game and then lastly in 2020 the decision not to introduce the circuit breaker in September or October what to introduce a test System earlier when the prevalence of the virus was lower for good or ill yesterday the rate of excess deaths in this country as I say, I think this is the statistics battery and I think that the every country struggled with a new plan and I think the the UK from the evidence that I have seen was well done the European table in the oldest even further down the road table if I have to answer why I think we faced particular Penguins, I would say it was Irrespective of of government action are we have a Coke and a we are in Europe that they don't help.

You, see extremely well aware of the arguments that the long-term decisions and sells cheap Nativity in individually contributed to the number of excess. What do you say to that I say that I don't know but I'm aware of the documents made. What would I would say respectfully to people is that? they were very very difficult decisions and the issue of the timeliness of a blank times was clearly one that we considered. Very hard at the time.

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